About: Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network.

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About: Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network. Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network.
Creator	Lumbreras, Carlos Manuel, José Miguel, Jose Aizpuru, Fonseca Arnalich Fernández, Francisco Castro, Freire Crestelo Vieitez, Anxela Miguel, Juan Perales Fraile, Isabel Santos, Antón Vargas Núñez, Juan Antonio, Juan Artero, Arturo Authors, José Bermejo, Lumbreras Bonet Tur, David Bruñén, García Carrasco Sánchez, Francisco Castro, Santiago Cat, Manuel David, José Del Pilar, María Fernández, Arnalich Fonseca Aizpuru, Eva Fraile, Perales Huelgas, Ricardo Javier, Franscisco Manuel, Casas Manzano, Luis Marquínez, Solís Millán Núñez-Cortés, Jesús Mora, Artero Moreno, Fidalgo Nataya, Marta Núñez, Vargas Núñez-Cortés, Millán Pejenaute, Rabadán Peña, Torres Pilar, Del Puchades, Francesc Rabadán Pejenaute, Elisa Ricardo Gómez, Rincón, Ramos Rodilla, Enrique Rojo, Rojo, Casas Roy-Vallejo, Emilia Rubio-Rivas, Manuel Sánchez, Carrasco Tur, Bonet Vieitez, Crestelo
Source	MedRxiv
abstract	Background. Spain has been one of the countries most affected by the COVID-19 pandemic. Objective. To create a registry of patients with COVID-19 hospitalized in Spain in order to improve our knowledge of the clinical, diagnostic, therapeutic, and prognostic aspects of this disease. Methods. A multicentre retrospective cohort study, including consecutive patients hospitalized with confirmed COVID-19 throughout Spain. Epidemiological and clinical data, additional tests at admission and at seven days, treatments administered, and progress at 30 days of hospitalization were collected from electronic medical records. Results. Up to April 30th 2020, 6,424 patients from 109 hospitals were included. Their median age was 69.1 years (range: 18-102 years) and 56.9% were male. Prevalences of hypertension, dyslipidemia, and diabetes mellitus were 50.2%, 39.7%, and 18.7%, respectively. The most frequent symptoms were fever (86.2%) and cough (76.5%). High values of ferritin (72.4%), lactate dehydrogenase (70.2%), and D-dimer (61.5%), as well as lymphopenia (52.6%), were frequent. The most used antiviral drugs were hydroxychloroquine (85.7%) and lopinavir/ritonavir (62.4%). 31.5% developed respiratory distress. Overall mortality rate was 21.1%, with a marked increase with age (50-59 years: 4.2%, 60-69 years: 9.1%, 70-79 years: 21.4%, 80-89 years: 42.5%, [≥] 90 years: 51.1%). Conclusions. The SEMI-COVID-19 Network provides data on the clinical characteristics of patients with COVID-19 hospitalized in Spain. Patients with COVID-19 hospitalized in Spain are mostly severe cases, as one in three patients developed respiratory distress and one in five patients died. These findings confirm a close relationship between advanced age and mortality.
has issue date	2020-05-26(xsd:dateTime)
bibo:doi	10.1101/2020.05.24.20111971
has license	medrxiv
sha1sum (hex)	06b506f55374a43a3b6a93dca8710242806673c6
schema:url	https://doi.org/10.1101/2020.05.24.20111971
resource representing a document's title	Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network.
resource representing a document's body	covid:06b506f55374a43a3b6a93dca8710242806673c6#body_text
is schema:about of	named entity 'Spain' covid:arg/06b506f55374a43a3b6a93dca8710242806673c6 named entity 'COVID-19' named entity 'patients' named entity 'Network' named entity 'Spain' named entity 'Spain' named entity 'COVID-19' named entity 'selection criteria' named entity 'pneumonia' named entity 'intensive care' named entity 'Antibiotics' named entity 'antiviral' named entity 'LDH' named entity 'COVID' named entity 'May 26' named entity 'COVID' named entity 'Italy' named entity 'Exclusion criteria' named entity 'SARS-COV-2' named entity 'Spain' named entity 'comorbidities' named entity 'physical examination findings' named entity 'ICU' named entity 'Demographic factors' named entity 'ICU' named entity 'respiratory impairment' named entity 'preprint' named entity 'AEMPS' named entity 'preprint' named entity 'SARS-CoV-2' named entity 'Madrid' named entity 'COVID' named entity 'selection bias' named entity 'real-time polymerase chain reaction'

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