About: Maternal antibody to infectious bronchitis virus: its role in protection against infection and development of active immunity to vaccine

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About: Maternal antibody to infectious bronchitis virus: its role in protection against infection and development of active immunity to vaccine Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Maternal antibody to infectious bronchitis virus: its role in protection against infection and development of active immunity to vaccine
Creator	Mondal, S Naqi, S
topic	covid:03e880c09dbfd6b00c9f5874fe37647be1cc55b5#this
Source	Elsevier; Medline; PMC
abstract	Chicks hatched with high levels of maternal antibody had excellent protection (>95%) against infectious bronchitis virus (IBV) challenge at 1 day of age, but not at 7 days (<30%). This protection significantly (P<0.05) correlated with levels of local respiratory antibody and not with serum antibody. A high percentage of both maternal antibody-positive (Mab+) and maternal antibody-negative (Mab−) chicks failed to produce IBV antibody when vaccinated at 1 day of age by the intraocular route. In addition, Mab+ chickens had a weaker virus-neutralizing antibody response to a second IBV vaccination compared to Mab− birds (P<0.05). Mab+ chicks experienced a more rapid decline (P<0.01) in maternal antibody after 1-day-of-age vaccination compared to their unvaccinated counterparts. A monoclonal antibody-based blocking ELISA that measured antibody levels specific to S1 glycoprotein of IBV correlated well with virus-neutralizing antibody titers.
has issue date	2001-05-10(xsd:dateTime)
bibo:doi	10.1016/s0165-2427(01)00248-3
bibo:pmid	11356248
has license	no-cc
sha1sum (hex)	03e880c09dbfd6b00c9f5874fe37647be1cc55b5
schema:url	https://doi.org/10.1016/s0165-2427%2801%2900248-3
resource representing a document's title	Maternal antibody to infectious bronchitis virus: its role in protection against infection and development of active immunity to vaccine
has PubMed Central identifier	PMC7119856
has PubMed identifier	11356248
schema:publication	Vet Immunol Immunopathol
resource representing a document's body	covid:03e880c09dbfd6b00c9f5874fe37647be1cc55b5#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/03e880c09dbfd6b00c9f5874fe37647be1cc55b5
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